
This occurs when the brain cannot produce enough corticotropin-releasing hormone (CRH). Without ACTH, the adrenals do not receive a signal to make cortisol. This occurs when the pituitary gland does not make enough of a hormone called adrenocorticotropin (ACTH).

This condition develops when the adrenal gland itself does not function well and cannot make enough cortisol.

Adrenal insufficiency and Addison’s disease

The following sections discuss the most common adrenal gland disorders. When this happens, it is known as an adrenal gland disorder. Sometimes, the adrenal glands produce too much or not enough of their hormones.
